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Huntingtons Disease > P53
The following information is about p53.
p53 Defined
One of the transcription factors that requires the presence of CBP in order to bind to DNA. An inability of P53 to access and bind to the DNA can lead to abnormal gene transcription and expression, ultimately leading to cell death.
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Off-site p53 Links, User Submitted
The following links have been collected through user bookmark submission in the p53 category. Please note, because these resources are off-site we cannot guarantee the accuracy or quality of any information.
Tue Jun 23
- Cell Death and Differentiatio n - The complexity of p53 stabilization and activation
- http://www.nat ure.com/onc/jo urnal/v17/n8/p df/1202014a.pd f: CK2 phosphorylates p53 at S392
- Casein kinase 2 inhibition decreases hypoxia-induci ble factor-1 activity under hypoxia through elevated p53 protein level -- Hubert et al. 119 (16): 3351 -- Journal of Cell Science
- COP9 signalosome-sp ecific phosphorylatio n targets p53 to degradation by the ubiquitin system
- Mutant p53 forms a complex with Sp1 on HIV-LTR DNA. [Biochem Biophys Res Commun. 2000] - PubMed Result
- Inhibition of HIV-1 replication by RNA interference of p53 expression -- Pauls et al. 80 (3): 659 -- Journal of Leukocyte Biology
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