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Sirtuins Defined

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Off-site Sirtuins Links, User Submitted

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Wed Jun 17

• Wistar institute team finds key target of aging regulator: Deacetylation of H4K16 by Sir2 and consequent telomere stability play a major role in maintaining long lifespan in yeast. Since sirtuins deacetylate many different proteins, these results clarify a key role of Sir2 protein in control of lifespan.

Wed Jun 10

• Links in the Science of Aging: good list of links...
• David A. Sinclair et al. Discover Three Classes of Molecules that Activate Sirtuins (Including Resveratrol)

Wed Apr 22

• The Achilles? Heel of Aging § SEEDMAGAZINE.C OM: "...a proven method to extend life already exists; scientists have known about it since the 1930s. It?s called calorie restriction, or CR. Feed a mouse a nutritious diet that has 30 percent fewer calories, and she lives 30 percent longer than the one in the next cage. Nor is she condemned to an extended, prolonged period of senescence; on less food, she lives longer and better, resistant to age-related diseases." ;

Tue Jan 27

• Fountain Of Youth In A Wine Rx?, Researchers Tell Morley Safer Red Wine Substance Resveratrol Could One Day Lengthen Lives - CBS News

Tue Dec 2

• Has universal ageing mechanism been found? - health - 26 November 2008 - New Scientist

Sun Nov 30

• Potentially Universal Mechanism Of Aging Identified: Annotated link http://www.dii go.com/bookmar k/http%3A%2F%2 Fwww.scienceda ily.com%2Frele ases%2F2008%2F 11%2F081126122 203.htm

Wed Nov 26

• How Cells Age - Technology Review: Another indication you need to get those doses of Resveratrol down!

Mon Nov 17

• Caloric Restriction Stimulates Angiogenesis Through Adiponectin

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