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Huntingtons Disease > Histone Acetyltransferases
The following information is about Histone Acetyltransferases.
Histone Acetyltransferases Defined
These enzymes add an acetyl group to histones, thus releasing the restricted access to DNA imposed by histones. Transcription factors can then bind to the DNA, allowing gene transcription to occur. Patients with HD tend to have decreased histone acetyltransferase activity.
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