The following information is about Caspase-3.

Caspase-3 Defined

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Off-site Caspase-3 Links, User Submitted

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Wed Aug 6

• Caspase-3 Antibody #9662

Fri Aug 17

• XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs
• Structural Basis for the Inhibition of Caspase-3 by XIAP
• NMR Structure and Mutagenesis of the Third Bir Domain of the Inhibitor of Apoptosis Protein XIAP -- Sun
• Cleavage of human inhibitor of apoptosis protein XIAP results in fragments with distinct specificities for caspases.
• A Single BIR Domain of XIAP Sufficient for Inhibiting Caspases -- Takahashi 1998
• The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. - Roy 1997: These were shown later to not be direct caspase inhibitors?

Tue Aug 14

• Caspase 3 activation is essential for efficient influenza virus propagation
• African Swine Fever Virus IAP Homologue Inhibits Caspase Activation and Promotes Cell Survival in Mammalian Cells

Mon Aug 13

• Characterizati on of the Apoptosis Suppressor Protein P49 from the Spodoptera littoralis Nucleopolyhedr ovirus -- Pei et al. 277 (50): 48677 -- Journal of Biological Chemistry

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Off-site Caspase-3 Research Links

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