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Tue Jun 30

• Zanni Group at University of Wisconsin-Madi son: Research in the Zanni group is aimed at exploring molecular structures and dynamics through vibrational motions and couplings. To accomplish this, sophisticated ultrafast multi-dimensio nal spectroscopies are being developed that correlate vibrational modes and measure frequency fluctuations. Emphasis is placed on understanding the molecular vibrations of complex biomolecules with regards to structure and function.
• UCLA-DOE - David Eisenberg: Our lab studies protein interactions using X-ray crystallograph y, computational analyses, and biochemical methods. We have a long-term goal of understanding and manipulating the functioning of cells through the interactions of their constituent proteins. X-ray crystallograph y is a powerful tool for exploring protein structure and interactions. The crystallograph y projects in our lab fall into two groups. The first focuses on amyloid and prions, classes of pathologically interacting proteins. Our goal is to understand the structures that underlie the pathologies. The second group studies the structural biology of Mycobacterium tuberculosis, with particular focus on protein-protei n complexes, as part of the TB Structural Genomics Consortium.

Wed Jun 3

• Weekly curry 'may fight dementia' - BBC NEWS | Health: Eating a curry once or twice a week could help prevent the onset of Alzheimer' ;s disease and dementia, a US researcher suggests. The key ingredient is curcumin, a component of the spice turmeric.

Mon May 18

• Epilepsy link to Alzheimer's may lead to better treatment - university of aberdeen: multi country trial journal of neurobiology The chemical, beta-amyloid, affects cognitive abilities in Alzheimer' ;s patients. It has now been discovered that it also makes nerve cells more sensitive and excitable. This prevents them from communicating properly with each other and leads to seizures

Tue May 12

• Article : SciBX: Science-Busine ss eXchange: A study by a team at Genentech Inc. proposes a new mechanism for Alzheimer' ;s disease pathogenesis by outlining a process that could be an early step in the neurodegenerat ive disorder. The work also identifies a trio of new AD targets, which the company is pursuing with preclinical programs. The study suggests that the previously ignored amino-terminal portion of amyloid precursor protein (APP), called N-APP, might be the main culprit behind AD. APP is a transmembrane protein that gives rise to N-APP and the much more commonly known -amyloid (A), a fragment that forms the amyloid fibers and plaques that are hallmarks of AD, although the precise role of those fibers and plaques in disease pathology is unclear.

Fri Apr 17

• Trojan Peptides Amyloid Beta Peptides Oxygen Peptide Synthesis ...: Bio-Synthesis Inc. is a leading life science products company which deals in Trojan Peptides, Amyloid Beta Peptides, Oxygen Peptide, Peptide Synthesis Chemistry, Peptide Synthesizers and Custom Peptide.

Sun Apr 5

• Self-Propagati ng, Molecular-Leve l Polymorphism in Alzheimer's {beta}-Amyloid Fibrils -- Petkova et al. 307 (5707): 262 -- Science: amyloid fibrils

Tue Mar 17

• New test can detect early Alzheimer's: study

Thu Feb 19

• NMR Knowledge Base - The NMR Resource

Sun Jan 25

• AD Destroying Amyloid Proteins With Lasers: tagging amyloid with fluorescent dye and visualising with lasers produced degradation-po ssibility for treatment Japan

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